Quick Navigation

Muscle Gain and Exercise

These supplements may affect the rate of muscle growth, the rate of muscle loss, or various aspects of exercise performance.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Are you looking to build muscle and improve exercise performance?

If you want simple and direct step-by-step directions on what works and what's a waste, then you need our Supplement Guides.

We tell you exactly what to take, how much to take, and when to take it. Our guides help you make sure you don't get overwhelmed with conflicting information, and are based on scientific research.

I want science-based recommendations »

Muscle Gain and Exercise Summary

These supplements may affect muscle mass or performance in athletic activities. Supplements that affect muscle mass may do so by affecting the rate of muscle protein synthesis and breakdown directly or indirectly — by influencing the amount of resistance exercise people are able to do. Supplements that affect exercise performance may do so by influencing energy production and usage or the fatiguing effects of exercise on muscular and neurological function.

Supplements in this category may be stimulatory, such as caffeine; increase ATP availability, such as creatine; reduce the oxygen requirements of metabolism and increase vasodilation, such as nitrate; increase muscle protein synthesis, such as protein powders; or reduce muscle soreness from exercise, such as certain antioxidants and anti-inflammatory compounds.

Are you looking to build muscle and improve exercise performance?

If you want simple and direct step-by-step directions on what works and what's a waste, then you need our Supplement Guides.

We tell you exactly what to take, how much to take, and when to take it. Our guides help you make sure you don't get overwhelmed with conflicting information, and are based on scientific research.

I want science-based recommendations »

Things To Know & Note

Also Known As

Non-caloric muscle builders, muscle builder

Do Not Confuse With

'Steroids', Performance Enhancer

Are you looking to build muscle and improve exercise performance?

If you want simple and direct step-by-step directions on what works and what's a waste, then you need our Supplement Guides.

We tell you exactly what to take, how much to take, and when to take it. Our guides help you make sure you don't get overwhelmed with conflicting information, and are based on scientific research.

I want science-based recommendations »

Get access to the latest research

By becoming an Examine.com Member, you'll have access to all of the latest nutrition research on over 300 supplements across over 500 different health goals, outcomes, conditions, and more.